Opioid Analgesics: Pain (algesia) is an unpleasant, ill-defined subjective symptom. It is usually evoked by an external or internal noxious stimulus. The pain inducing endogenous substances are called algogenic agents. They are released during ischaemia, inflammation, tissue injury, and by thermal or mechanical stimuli. These algogenic agents are acetyicholine, histamine,… Continue Reading Opioid Analgesics

Nausea is a desire to vomit. It may or may not culminate in vomiting. Emesis or vomiting is a protective mechanism. It serves to eliminate harmful substances from the stomach and duodenum. Emesis is a coordinated act of medullary vomiting centre (VC) and the chemoreceptor trigger zone (CTZ), situated fri… Continue Reading Emetics, Antiemetics and other Gastrointestinal Drugs

Frequent passage of liquid or semisolid stools is called diarrhea. This can be cured by using drugs for Diarrhea.It maybe accompanied by abdominal pain. It can be caused by enteric infection, food toxins, malnutrition, inflammation and drugs like reserpine, synthetic prostaglandins, metoclopramide, domperidon, cholinergic drugs, quinidine and purgatives. Dysentery is… Continue Reading Drugs for Diarrhea