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Monthly Archives: September 2012

Autoimmune Hepatitis Chronic Active

Autoimmune hepatitis (AIH) is a disease characterized by irresolving inflammation of the liver, a predominant pen portal. Hepatitis which generally involves young women who are well nourished with moon facies, acne, amenorrhea hirsuties, pigmentation and abdominal striae. Onset is insidious and patient may be asymptomatic for number of years. Patient …

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Autoimmune disorders or diseases

Autoimmune disorders – An agent capable of stimulating immune response is known as antigen. It may be a protein, polysaccharide or a complex lipid. There are two kinds of immune responses. Humoral immune response involved in the production of antibodies and cellular immunity in which incompetent cells react directly against …

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Dermatomyositis and Polymyositis

Polymyositis is a immune mediated disorder of unknown aetiology. It is characterized by proximal muscular weakness and inflammatory and degenerative lesions of the striated muscles. When it is accompanied by skin lesions, it is called dermatomyositis. It is not a very common disease and mainly involves adults in the age …

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Polyarteritis nodosa

Polyarteritis nodosa is an uncommon connective tissue disorder, characterized by involvement of small and medium sized arteries. There is necrotizing vasculitis with polymorphonuclear infiltration, necrosis and aneursymal dilatation of the vessel wall. The involvement of vessels is widespread and involves major organs except pulmonary vessels. It is a rare disease which …

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Scleroderma (systemic sclerosis)

Scleroderma (systemic sclerosis) is a disease of unknown etiology and is of worldwide distribution. Women are affected more as compared to men (3: 1) and are usually seen after the age of 30 years. Its onset in childhood is unusual. It is characterized by thickening and fibrosis of the skin, …

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Systemic Lupus Erythematosis (SLE)

Systemic Lupus Erythematosis (SLE) is an autoimmune disorder of connective tissue with multi-system involvement and usually proceeds by remissions and relapses. It may begin insidiously or acutely and subacutely. Many cases present with arthralgia for months before characteristic rashes appear and suspicion about the disease is entertained. Systemic Lupus Erythematosis (SLE) …

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Connective Tissue Disorders

Connective Tissue Disorders are a group of disorders which are characterized by arthralgia, arthritis, myositis, raynauds phenomenon and skin lesions. There is multi system involvement with fibrinoid degeneration of connective tissue. Most Connective Tissue Disorders are common in women and these include systemic lupus erythematosis and Sjogren’s syndrome while in men vasculatides …

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Ankylosing spondylitis (marie-strupell disease)

It is a chronic progressive inflammatory disorder of unknown etiology, distinguished by the involvement of sacroiliac joints, synovial and spinal joints and the adjacent soft tissues. There may be associated involvement of peripheral joints and extra-articular structures. It is often referred to as rheumatoid spondylitis (Bambo spine). The disease is …

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Lumbar spondylosis

Lumbar spondylosis comprises degenerative disorder of the lumbo sacral region of the spine and is referred to as lumbago, sciatica or prolapse intravertebral disc (PID). There is intervertebial disc degeneration osteophyte formation and pain in low back, radiating down to lower extremities. The spinal column is well adapted to various wears …

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