It is now agreed that Disease modifying anti rheumatic drugs (DMARDS) should be started early in disease i.e. within 3-6 months of onset of symptoms when patient has persistent polyarticular synovitis, joint deformity and reduction in functional capacity. Traditionally patients are put on Disease modifying anti rheumatic drugs (DMARDS) when they fail… Continue Reading Disease modifying anti rheumatic drugs (DMARDS)

Neurological tests are some of the most common tests done throughout the world. Nervous system constitutes a major part of the body and its correct functioning is essential for the maintenance of quality of life. A number of disorders affect the mind, cerebral cortex, cerebellum, peripheral nerves and all associated… Continue Reading Neurological tests (CT scan, MRI, ECG, angiography, Xray, Electromyogram)

The Glucocorticoids influence carbohydrate and protein metabolism whereas the mineralocorticoids affect water and electrolyte balance. Glucocorticoids enter target cells by diffusion and bind to specific receptors present in the cell nucleus. Thus they regulate protein synthesis by stimulating messenger RNA formation. Partly the metabolic effects of glucocorticoids may be due… Continue Reading Glucocorticoids

Antihistamines – There are two types of histamine antagonists namely H1 receptor antagonists (classical type) and H2 receptor antagonists (used in peptic ulcer). Only H1 receptor antagonists are described below and 112 receptor antagonists will be discussed along with other drugs used for the treatment of peptic ulcer. H1 antihistamines antagonists act by… Continue Reading Antihistamines

Drugs used for the treatment of Hyperlipidemia are called Antihyperlipidemic. The aim of the treatment is to lower the concentration of VLDL and LDL and raise HDL. 1.  Antihyperlipidemic Drugs which Primarily Reduce Plasma Triglycerides i. Nicotinic acid (niacin, B3): It is a water soluble vitamin. It lowers plasma triglyceride levels.… Continue Reading Antihyperlipidemic drugs reduce Plasma Triglycerides & Cholesterol

Vaccines for children may be broadly classified as Essential (EPI) vaccines included in national immunization schedule – BCG, OPV, DPT, Measles and Hepatitis B, Recommended or Optional vaccines e.g. MMR, H. influenza B, Typhoid, Hepatitis A, Varicella, Vaccine for selective use e.g. High-risk children: Pneumococci, Meningococci, influenza virus Post-exposure: Anti-rabies vaccine and Combination Vaccines & Newer… Continue Reading Vaccines for children

Typhoid vaccination are of three types that are Whole-cell inactivated vaccines, Live attenuated oral vaccine (Ty2 1 strain), and parenteral Vi capsular polysaccharide vaccine. However, only the polysaccharide vaccine is currently available in Asian countries. Contents: Each dose contains 25 mgIO.5 ml of capsular polysaccharide units (Vi antigen). Supply &… Continue Reading Typhoid vaccination

BCG Vaccine (Bacillus Calmatte Guerin vaccine) is the oldest amongst currently used vaccines (earliest vaccine was small pox, used in 1798), named after its developing scientists – Leon Charles Albert Calmette and Camille Guerin (1921). Contents of BCG Vaccine: It is a live attenuated vaccine containing 0.1- 0.4 million viable… Continue Reading Bcg vaccine and its side effects