Category Archives: Drugs & Meds

Disease modifying anti rheumatic drugs (DMARDS)

It is now agreed that Disease modifying anti rheumatic drugs (DMARDS) should be started early in disease i.e. within 3-6 months of onset of symptoms when patient has persistent polyarticular synovitis, joint deformity and reduction in functional capacity. Traditionally patients are put on Disease modifying anti rheumatic drugs (DMARDS) when they fail to respond to NSAIDs. Now… Read More »

Antihistamines

Antihistamines – There are two types of histamine antagonists namely H1 receptor antagonists (classical type) and H2 receptor antagonists (used in peptic ulcer). Only H1 receptor antagonists are described below and 112 receptor antagonists will be discussed along with other drugs used for the treatment of peptic ulcer. H1 antihistamines antagonists act by competitively blocking the histamine receptors.… Read More »

Vaccines for children

Vaccines for children may be broadly classified as Essential (EPI) vaccines included in national immunization schedule – BCG, OPV, DPT, Measles and Hepatitis B, Recommended or Optional vaccines e.g. MMR, H. influenza B, Typhoid, Hepatitis A, Varicella, Vaccine for selective use e.g. High-risk children: Pneumococci, Meningococci, influenza virus Post-exposure: Anti-rabies vaccine and Combination Vaccines & Newer vaccines. ESSENTIAL (EPI) Vaccines for… Read More »

Typhoid vaccination

Typhoid vaccination are of three types that are Whole-cell inactivated vaccines, Live attenuated oral vaccine (Ty2 1 strain), and parenteral Vi capsular polysaccharide vaccine. However, only the polysaccharide vaccine is currently available in Asian countries. Contents: Each dose contains 25 mgIO.5 ml of capsular polysaccharide units (Vi antigen). Supply & storage: It is supplied as… Read More »

Measles vaccine

Measles vaccine is available as a single disease vaccine or in combination with mumps and rubella. Contents: It is a live attenuated vaccine prepared from Edmonston-Zagreb or Schwarz strain, containing 1000 TCID50/dose. Supply & storage of Measles vaccine: It is available as single dose or multi- dose vial containing lyophilized powder, along with a diluent and should… Read More »

Oral polio vaccine

Oral polio vaccine (OPV): Two types of polio vaccines are available – a live, oral, Sabin vaccine and an inactivated, parenteral Salk vaccine, named after their developers. In India, OPV is used under NIS. Contents – OPV is a live attenuated, polyvalent vaccine, containing three strains of virus – I, II, and III, in concentrations… Read More »

Bcg vaccine and its side effects

BCG Vaccine (Bacillus Calmatte Guerin vaccine) is the oldest amongst currently used vaccines (earliest vaccine was small pox, used in 1798), named after its developing scientists – Leon Charles Albert Calmette and Camille Guerin (1921). Contents of BCG Vaccine: It is a live attenuated vaccine containing 0.1- 0.4 million viable bacilli per dose, In India,… Read More »