Gout is a disorder of purine metabolism which is characterized by increased urate levels in the blood, recurrent attacks of acute arthritis and deposition of monosodium urate monohydrate in and around the joints. These vary from 2-7 mg/dl and levels above 7.0 mgldl in men and 6.0 mg/dl in women denotes… Continue Reading Gout – features, pathology, diagnosis, investigations, treatment

Osteoarthritis is a slowly evolving chronic degenerative disease which disables people in mid forties, is widely prevalent all over the world and is characterized by pain and discomfort round big joints making the life of individual miserable. It is a continuous process of aging where the normal repair mechanism of… Continue Reading Osteoarthritis – factors, pathology, clinical picture, diagnosis, treatment

Gonococcal arthritis  is an important form of arthritis which involves young adults of either sex who indulge in sexual abuse. About 2-5% of those suffering from gonorrhoea develop this complication. Clinically patient presents with fever, mild inflammatory asymmetrical polyarthritis with migratory joint paths. There is painful tenosynovitis. The joints mainly… Continue Reading Gonococcal Meningococcal arthritis

Rheumatoid arthritis occurring in children below 14 years of age constitutes Juvenile Rheumatoid arthritis and is part of the disease process which goes ultimately into the adult from of disease. It may appear at any age in childhood but most cases are seen between 1-5 years of age, girls being… Continue Reading Juvenile rheumatoid arthritis & Non-gonococcal acute infectious arthritis

It is now agreed that Disease modifying anti rheumatic drugs (DMARDS) should be started early in disease i.e. within 3-6 months of onset of symptoms when patient has persistent polyarticular synovitis, joint deformity and reduction in functional capacity. Traditionally patients are put on Disease modifying anti rheumatic drugs (DMARDS) when they fail… Continue Reading Disease modifying anti rheumatic drugs (DMARDS)

Rheumatoid arthritis is a chronic immune-inflammatory disease which affects peripheral joints in a symmetrical manner producing inflammatory changes, with cartilage destruction, bony erosions and resultant bone deformities and systemic manifestations which occur in a fair percentage of cases. The prevalence of the disease is worldwide and approximately one percent of… Continue Reading Rheumatoid arthritis – diagnosis, pathology, features and treatment

Rheumatology comprises diseases which primarily affect joints and connective tissue consisting mainly of skin and tendons. It is a multi system involvement and has diseases which have common properties and one feature common in all of them is that symptoms or findings are referable to the joints or adjacent tissues at… Continue Reading Rheumatology and Diseases of Joints